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Co-Authors
- Anubhav Mishra
- Girish Sahu
- Amit Kumar
- Ghanshyam Rathore
- Dileshwar Sahu
- Ravindra
- Manmohan Diwan
- Dhaniram Kanwar
- Laxminarayan Patel
- Mukta Agrawal
- D. K. Tripathi
- Ajazuddin
- Amit Alexander
- Amrita Thakur
- Nisha Nair
- Yashi Thakur
- Juhi Thakur
- Teman Nirmalkar
- Ved Prakash Verma
- Vibhash Gupta
- Vivek Singh Yadav
- Kalpana Mahilange
- Pooja Mahant
- Pritam Yadav
- Dinesh Khamari
- Jyotsana Meshram
- Rakesh Sahu
- Tarun Ghatode
- Ajazuddin
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Patel, Deepak
- Underlining the Pharmaceutical Aspects Associated with the Development of pH Responsive Hydrogel
Abstract Views :146 |
PDF Views:1
Authors
Anubhav Mishra
1,
Girish Sahu
1,
Amit Kumar
1,
Deepak Patel
1,
Ghanshyam Rathore
1,
Dileshwar Sahu
1,
Ravindra
1,
Manmohan Diwan
1,
Dhaniram Kanwar
1,
Laxminarayan Patel
1,
Mukta Agrawal
1,
D. K. Tripathi
1,
Ajazuddin
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 4 (2017), Pagination: 1261-1268Abstract
Controlled drug delivery is useful because it allows obtaining better drug product, effectiveness, reliability and safety. Hydrogel are one of the upcoming classes of polymer-based controlled release drug delivery systems. Besides exhibiting swelling-controlled drug release, hydrogel also show stimuli-responsive changes in their structural network and hence, the drug release. Because of large variations in physiological pH at various body sites in normal as well as pathological conditions, pH-responsive polymeric networks have been extensively studied. This review highlights the use of hydrogel (a class of polymeric systems) in controlled drug delivery, and their application in pH-responsive, drug release. Hydrogel show minimal tendency to adsorb proteins from body fluids because of their low interfacial tension. Further, the ability of molecules of different sizes to diffuse into (drug loading) and out of (drug release) hydrogel allows the possible use of dry or swollen polymeric networks as drug delivery systems for oral, nasal, buccal, rectal, vaginal, ocular and parenteral routes of administration. Hydrogel also terms 'intelligent gels' or 'smart hydrogel'. The smartness of any material is the key to its ability to receive, transmit or process a stimulus, and respond by producing a useful effect. This review highlights the use of hydrogel (a class of polymeric systems) in controlled drug delivery, and their application in stimuli responsive, especially pH-responsive, drug release. In this review article, the various aspects of pharmaceutical microemulsin where compile together and the target audience are specifically the M.pharm and B.pharm student so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.Keywords
Hydrogel, Stimuli-Responsive, Smart Hydrogel.- Formulation Aspects Behind the Development of a Stable Biphasic Liquid Dosage Form with Special Reference to Microemulsion: A Review
Abstract Views :463 |
PDF Views:0
Authors
Amrita Thakur
1,
Nisha Nair
1,
Mukta Agrawal
1,
Yashi Thakur
1,
Juhi Thakur
1,
Teman Nirmalkar
1,
Ved Prakash Verma
1,
Vibhash Gupta
1,
Vivek Singh Yadav
1,
Kalpana Mahilange
1,
Pooja Mahant
1,
Pritam Yadav
1,
Deepak Patel
1,
Dinesh Khamari
1,
Jyotsana Meshram
1,
Rakesh Sahu
1,
Tarun Ghatode
1,
D. K. Tripathi
1,
Ajazuddin
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 114-118Abstract
A plethora of research and industrial processes used microemulsion system after its discovery by Jack H. Shulman. The microemulsionis defined as clear, stable, isotropic mixtures of oil, water, and surfactant, frequently in combination with a co-surfactant. They are solutions of oil, water,andamphiphile which are optically isotropic and thermodynamically stable. The aqueous phase present in the system contains salt(s) and other ingredients while the "oil" phase mainly forms a complex of different hydrocarbons and olefins. They do not require high shear conditions as compared to ordinary emulsions. Hence they are easy to prepare. Ultralow interfacial tension, large interfacial area, thermodynamic stability and the ability to solubilize immiscible liquids are some of its unique properties. They also show the ability to protect labile drug, control drug release, increase drug solubility, increase bioavailability and reduce patient variability. Hence, microemulsion has gained most significance in both basictypes of research as well as in industry. They have wide applications and uses such as in pharmaceuticals, cosmetics, cutting oils, biotechnology, food, agrochemicals, environmental detoxification, analytical applications, microporous media synthesis, etc. The microemulsion can be effectively used in dermal delivery because of its mechanism, hence can be used in pharmaceutical and cosmetics preparation. Microemulsion enhances the dermal absorption as they allow rapid penetration of active molecules due to the large surface area of the internal phase and their components reduce the barrier of stratum corneum. Thus, microemulsionisa promising vehicle for effective drug delivery. The current review article deals with information about the microemulsion. Also, the present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
Microemulsion, Thermodynamically Stable, Bioavailability.References
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